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Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Vandekeere, Saar; Dubois, Charlotte; Kalucka, Joanna; Sullivan, Mark R; García-Caballero, Melissa; Goveia, Jermaine; Chen, Rongyuan; Diehl, Frances F; Bar-Lev, Libat; Souffreau, Joris; Pircher, Andreas; Kumar, Saran; Vinckier, Stefan; Hirabayashi, Yoshio; Furuya, Shigeki; Schoonjans, Luc; Eelen, Guy; Ghesquière, Bart; Keshet, Eli; Li, Xuri; Vander Heiden, Matthew G; Dewerchin, Mieke; Carmeliet, Peter.
Afiliación
  • Vandekeere S; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, VIB-K
  • Dubois C; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Kalucka J; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Sullivan MR; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • García-Caballero M; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Goveia J; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Chen R; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China.
  • Diehl FF; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Bar-Lev L; Department of Developmental Biology and Cancer Research, The Hebrew University, Jerusalem 91120, Israel.
  • Souffreau J; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Pircher A; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Kumar S; Department of Developmental Biology and Cancer Research, The Hebrew University, Jerusalem 91120, Israel.
  • Vinckier S; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Hirabayashi Y; Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute, Wako City, Saimata 351-0198, Japan.
  • Furuya S; Department of Bioscience and Biotechnology, Kyushu University, Fukuoka 812-8581, Japan.
  • Schoonjans L; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, VIB-K
  • Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Ghesquière B; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium.
  • Keshet E; Department of Developmental Biology and Cancer Research, The Hebrew University, Jerusalem 91120, Israel.
  • Li X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China. Electronic address: lixr6@mail.sysu.edu.cn.
  • Vander Heiden MG; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, VIB-KU Leuven Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium. Electronic address: mieke.dewerchin@kule
  • Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, VIB-K
Cell Metab ; 28(4): 573-587.e13, 2018 10 02.
Article en En | MEDLINE | ID: mdl-30017355
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Serina / Células Endoteliales / Fosfoglicerato-Deshidrogenasa / Hemo Límite: Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2018 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Serina / Células Endoteliales / Fosfoglicerato-Deshidrogenasa / Hemo Límite: Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2018 Tipo del documento: Article