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Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL-12p70 production and mediate elevated effector functions in innate and adaptive immune cells.
Sköld, Annette E; Mathan, Till S M; van Beek, Jasper J P; Flórez-Grau, Georgina; van den Beukel, Michelle D; Sittig, Simone P; Wimmers, Florian; Bakdash, Ghaith; Schreibelt, Gerty; de Vries, I Jolanda M.
Afiliación
  • Sköld AE; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • Mathan TSM; Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden.
  • van Beek JJP; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • Flórez-Grau G; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • van den Beukel MD; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • Sittig SP; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • Wimmers F; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • Bakdash G; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • Schreibelt G; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Geert Grooteplein 26/28, 6525 GA, Nijmegen, The Netherlands.
  • de Vries IJM; Allergic Inflammation Discovery Performance Unit, Respiratory Therapy Area, GlaxoSmithKline, Stevenage, United Kingdom.
Cancer Immunol Immunother ; 67(9): 1425-1436, 2018 Sep.
Article en En | MEDLINE | ID: mdl-30019146
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Dendríticas / Interferón Tipo I / Interleucina-12 / Células Mieloides Límite: Humans Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Dendríticas / Interferón Tipo I / Interleucina-12 / Células Mieloides Límite: Humans Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos