Your browser doesn't support javascript.
loading
Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs.
Chen, Helen Y; Plummer, Christopher W; Xiao, Dong; Chobanian, Harry R; DeMong, Duane; Miller, Michael; Trujillo, Maria E; Kirkland, Melissa; Kosinski, Daniel; Mane, Joel; Pachanski, Michele; Cheewatrakoolpong, Boonlert; Di Salvo, Jerry; Thomas-Fowlkes, Brande; Souza, Sarah; Tatosian, Daniel A; Chen, Qing; Hafey, Michael J; Houle, Robert; Nolting, Andrew F; Orr, Robert; Ehrhart, Juliann; Weinglass, Adam B; Tschirret-Guth, Richard; Howard, Andrew D; Colletti, Steven L.
Afiliación
  • Chen HY; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Plummer CW; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Xiao D; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Chobanian HR; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • DeMong D; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Miller M; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Trujillo ME; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Kirkland M; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Kosinski D; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Mane J; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Pachanski M; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Cheewatrakoolpong B; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Di Salvo J; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Thomas-Fowlkes B; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Souza S; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Tatosian DA; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Chen Q; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Hafey MJ; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Houle R; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Nolting AF; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Orr R; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Ehrhart J; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Weinglass AB; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Tschirret-Guth R; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Howard AD; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
  • Colletti SL; Departments of Discovery Chemistry, Process Chemistry, Pharmacokinetics, Pharmacodynamics and Drug Metabolism, In Vivo Pharmacology, and In Vitro Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
ACS Med Chem Lett ; 9(7): 685-690, 2018 Jul 12.
Article en En | MEDLINE | ID: mdl-30034601
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos