Intestine-specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet-induced barrier dysfunction and glucose intolerance.

Ghosh, Siddhartha S; He, Hongliang; Wang, Jing; Korzun, William; Yannie, Paul J; Ghosh, Shobha

Ghosh, Siddhartha S; He, Hongliang; Wang, Jing; Korzun, William; Yannie, Paul J; Ghosh, Shobha.

Afiliación

Ghosh SS; Department of Internal Medicine, VCU Medical Center, Richmond, Virginia.
He H; Department of Internal Medicine, VCU Medical Center, Richmond, Virginia.
Wang J; Department of Internal Medicine, VCU Medical Center, Richmond, Virginia.
Korzun W; Department of Clinical and Laboratory Sciences, VCU Medical Center, Richmond, Virginia.
Yannie PJ; Hunter Homes McGuire VA Medical Center, Richmond, Virginia.
Ghosh S; Department of Internal Medicine, VCU Medical Center, Richmond, Virginia.

Physiol Rep ; 6(14): e13790, 2018 07.

Article en En | MEDLINE | ID: mdl-30058275

Asunto(s)

Fosfatasa Alcalina/metabolismo; Dieta Occidental/efectos adversos; Intolerancia a la Glucosa/metabolismo; Mucosa Intestinal/metabolismo; Fosfatasa Alcalina/genética; Animales; Células Cultivadas; Toxina del Cólera/metabolismo; Colesterol/efectos adversos; Intolerancia a la Glucosa/etiología; Intolerancia a la Glucosa/genética; Haptoglobinas; Humanos; Mucosa Intestinal/patología; Ratones; Ratones Endogámicos BALB C; Ratones Endogámicos C57BL; Precursores de Proteínas

Palabras clave

Glucose intolerance; Intestinal alkaline phosphatase; Intestinal barrier function; Western diet; zonulin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Intolerancia a la Glucosa / Fosfatasa Alcalina / Dieta Occidental / Mucosa Intestinal Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Physiol Rep Año: 2018 Tipo del documento: Article

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