Your browser doesn't support javascript.
loading
Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle.
Mackman, Richard L; Steadman, Victoria A; Dean, David K; Jansa, Petr; Poullennec, Karine G; Appleby, Todd; Austin, Carol; Blakemore, Caroline A; Cai, Ruby; Cannizzaro, Carina; Chin, Gregory; Chiva, Jean-Yves C; Dunbar, Neil A; Fliri, Hans; Highton, Adrian J; Hui, Hon; Ji, Mingzhe; Jin, Haolun; Karki, Kapil; Keats, Andrew J; Lazarides, Linos; Lee, Yu-Jen; Liclican, Albert; Mish, Michael; Murray, Bernard; Pettit, Simon B; Pyun, Peter; Sangi, Michael; Santos, Rex; Sanvoisin, Jonathan; Schmitz, Uli; Schrier, Adam; Siegel, Dustin; Sperandio, David; Stepan, George; Tian, Yang; Watt, Gregory M; Yang, Hai; Schultz, Brian E.
Afiliación
  • Mackman RL; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Steadman VA; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Dean DK; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Jansa P; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Poullennec KG; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Appleby T; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Austin C; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Blakemore CA; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Cai R; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Cannizzaro C; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Chin G; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Chiva JC; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Dunbar NA; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Fliri H; Cypralis Ltd. , Babraham Research Campus, Cambridge CB22 3AT , United Kingdom.
  • Highton AJ; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Hui H; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Ji M; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Jin H; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Karki K; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Keats AJ; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Lazarides L; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Lee YJ; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Liclican A; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Mish M; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Murray B; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Pettit SB; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Pyun P; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Sangi M; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Santos R; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Sanvoisin J; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Schmitz U; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Schrier A; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Siegel D; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Sperandio D; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Stepan G; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Tian Y; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Watt GM; Selcia Ltd. , Fyfield Business and Research Park, Fyfield Road , Ongar , Essex CM5 0GS , United Kingdom.
  • Yang H; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
  • Schultz BE; Gilead Sciences Inc. , 333 Lakeside Drive , Foster City , California 94404 , United States.
J Med Chem ; 61(21): 9473-9499, 2018 11 08.
Article en En | MEDLINE | ID: mdl-30074795
Asunto(s)
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diseño de Fármacos / Ciclofilinas / Inhibidores Enzimáticos Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diseño de Fármacos / Ciclofilinas / Inhibidores Enzimáticos Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos