Migraine is associated with high brain 5-HT levels as indexed by 5-HT<sub>4</sub> receptor binding.

Deen, Marie; Hougaard, Anders; Hansen, Hanne D; Svarer, Claus; Eiberg, Hans; Lehel, Szabolcs; Knudsen, Gitte M; Ashina, Messoud

Migraine is associated with high brain 5-HT levels as indexed by 5-HT₄ receptor binding.

Deen, Marie; Hougaard, Anders; Hansen, Hanne D; Svarer, Claus; Eiberg, Hans; Lehel, Szabolcs; Knudsen, Gitte M; Ashina, Messoud.

Afiliación

Deen M; 1 Danish Headache Center and Department of Neurology, Rigshospitalet Glostrup, Glostrup, Denmark.
Hougaard A; 2 Neurobiology Research Unit and NeuroPharm, Department of Neurology, Rigshospitalet, Copenhagen, Denmark.
Hansen HD; 3 Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Svarer C; 1 Danish Headache Center and Department of Neurology, Rigshospitalet Glostrup, Glostrup, Denmark.
Eiberg H; 2 Neurobiology Research Unit and NeuroPharm, Department of Neurology, Rigshospitalet, Copenhagen, Denmark.
Lehel S; 2 Neurobiology Research Unit and NeuroPharm, Department of Neurology, Rigshospitalet, Copenhagen, Denmark.
Knudsen GM; 4 Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ashina M; 5 PET and Cyclotron Unit, Rigshospitalet, Copenhagen, Denmark.

Cephalalgia ; 39(4): 526-532, 2019 04.

Article en En | MEDLINE | ID: mdl-30089402

Asunto(s)

Encéfalo/metabolismo; Radioisótopos de Carbono/metabolismo; Trastornos Migrañosos/metabolismo; Tomografía de Emisión de Positrones/métodos; Receptores de Serotonina 5-HT4/metabolismo; Serotonina/metabolismo; Adulto; Encéfalo/diagnóstico por imagen; Estudios Transversales; Femenino; Heterocigoto; Humanos; Masculino; Persona de Mediana Edad; Trastornos Migrañosos/diagnóstico por imagen; Trastornos Migrañosos/genética; Piperidinas/metabolismo; Unión Proteica/fisiología; Receptores de Serotonina 5-HT4/genética; Adulto Joven

Palabras clave

CNS; Headache; PET; chronic migraine; neuroimaging; pain

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Radioisótopos de Carbono / Serotonina / Receptores de Serotonina 5-HT4 / Tomografía de Emisión de Positrones / Trastornos Migrañosos Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Cephalalgia Año: 2019 Tipo del documento: Article País de afiliación: Dinamarca

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