Breast Cancer Stem Cells and Sex Steroid Hormones.
Curr Stem Cell Res Ther
; 14(5): 398-404, 2019.
Article
en En
| MEDLINE
| ID: mdl-30095060
Breast cancer stem cells (BCSCs) are a small population of tumor-initiating cells that express stem cell-associated markers. In recent years, their properties and mechanisms of regulation have become the focus of intense research due to their intrinsic resistance to conventional cancer therapies. This review describes breast cancer stem cell origin, signaling pathways involved in self-renewal, such as Wnt, Notch and Hedgehog, biomarkers linked to stemness, and the role of sex steroid hormones in BCSC regulation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hormonas Esteroides Gonadales
/
Células Madre Neoplásicas
/
Neoplasias de la Mama
/
Transducción de Señal
/
Autorrenovación de las Células
Límite:
Animals
/
Female
/
Humans
Idioma:
En
Revista:
Curr Stem Cell Res Ther
Asunto de la revista:
TERAPEUTICA
Año:
2019
Tipo del documento:
Article