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Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites.
Rangarajan, Sneha; He, Yanan; Chen, Yihong; Kerzic, Melissa C; Ma, Buyong; Gowthaman, Ragul; Pierce, Brian G; Nussinov, Ruth; Mariuzza, Roy A; Orban, John.
Afiliación
  • Rangarajan S; From the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850.
  • He Y; the Departments of Cell Biology and Molecular Genetics and.
  • Chen Y; From the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850.
  • Kerzic MC; Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, and.
  • Ma B; From the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850.
  • Gowthaman R; From the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850.
  • Pierce BG; the Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702.
  • Nussinov R; From the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850.
  • Mariuzza RA; the Departments of Cell Biology and Molecular Genetics and.
  • Orban J; From the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland 20850.
J Biol Chem ; 293(41): 15991-16005, 2018 10 12.
Article en En | MEDLINE | ID: mdl-30135211
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígeno HLA-A2 / Productos del Gen tax / Receptores de Antígenos de Linfocitos T alfa-beta / Complejo Receptor-CD3 del Antígeno de Linfocito T Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígeno HLA-A2 / Productos del Gen tax / Receptores de Antígenos de Linfocitos T alfa-beta / Complejo Receptor-CD3 del Antígeno de Linfocito T Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article