Your browser doesn't support javascript.
loading
HLA-IMPUTER: an easy to use web application for HLA imputation and association analysis using population-specific reference panels.
Shen, Jiangshan J; Yang, Chao; Wang, Yong-Fei; Wang, Ting-You; Guo, Mengbiao; Lau, Yu Lung; Zhang, Xuejun; Sheng, Yujun; Yang, Wanling.
Afiliación
  • Shen JJ; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR China.
  • Yang C; Department of Dermatology, No. 1 Hospital and Key Laboratory of Dermatology, Ministry of Education, Anhui Medical University, Hefei, China.
  • Wang YF; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR China.
  • Wang TY; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR China.
  • Guo M; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR China.
  • Lau YL; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR China.
  • Zhang X; Department of Dermatology, No. 1 Hospital and Key Laboratory of Dermatology, Ministry of Education, Anhui Medical University, Hefei, China.
  • Sheng Y; Department of Dermatology, No. 1 Hospital and Key Laboratory of Dermatology, Ministry of Education, Anhui Medical University, Hefei, China.
  • Yang W; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR China.
Bioinformatics ; 35(7): 1244-1246, 2019 04 01.
Article en En | MEDLINE | ID: mdl-30169743
ABSTRACT

SUMMARY:

HLA allele imputation from SNP genotypes has become increasingly useful, but its accuracy is heavily dependent on the reference panels used. HLA-IMPUTER implements HIBAG algorithm for HLA imputation with different population specific reference panels, including a new Han Chinese reference panel derived from 10 689 samples. We provide a convenient platform for researchers to impute HLA alleles and perform association analysis. AVAILABILITY AND IMPLEMENTATION http//wyanglab.org 3838/RefPanelWebsite/. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Asunto(s)
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Programas Informáticos / Polimorfismo de Nucleótido Simple Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Programas Informáticos / Polimorfismo de Nucleótido Simple Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2019 Tipo del documento: Article