Multimodal localization and surgery for epileptic spasms of focal origin: a review.
Neurosurg Focus
; 45(3): E4, 2018 09.
Article
en En
| MEDLINE
| ID: mdl-30173609
ABSTRACT
Epileptic spasms (ES) are a common manifestation of intractable epilepsy in early life and can lead to devastating neurodevelopmental consequences. Epilepsy surgery for ES is challenging because of inherent difficulties in localizing the epileptogenic zone in affected infants and children. However, recent clinical series of resective neurosurgery for ES suggest that not only is surgery a viable option for appropriately selected patients, but postoperative seizure outcomes can be similar to those achieved in other types of focal epilepsy. Increased awareness of ES as a potentially focal epilepsy, along with advances in neuroimaging and invasive monitoring technologies, have led to the ability to surgically treat many patients with ES who were previously not considered surgical candidates. In this study, the authors review the current state of epilepsy surgery for ES. Specifically, they address how advances in neuroimaging and invasive monitoring have facilitated patient selection, presurgical evaluation, and ultimately, resection planning.
Palabras clave
ACTH = adrenocorticotropic hormone; DE = depth electrode; EEG = electroencephalography; ES = epileptic spasms; EZ = epileptogenic zone; FDG = fluorodeoxyglucose; ILAE = International League Against Epilepsy; IS = infantile spasms; MEG = magnetoencephalography; SDE = subdural electrode; SEEG = stereoelectroencephalography; VEEG = video EEG; development; epilepsy; infantile spasms; pediatric neurology; pediatric neurosurgery; seizures
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Epilepsias Parciales
/
Procedimientos Neuroquirúrgicos
/
Imagen Multimodal
/
Epilepsia Refractaria
Límite:
Humans
Idioma:
En
Revista:
Neurosurg Focus
Asunto de la revista:
NEUROCIRURGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Canadá