Genome-wide DNA methylation profiling of primary colorectal laterally spreading tumors identifies disease-specific epimutations on common pathways.

Zhu, Liangliang; Yan, Feihu; Wang, Zhen; Dong, Haiyan; Bian, Chengling; Wang, Ting; Yu, Enda; Li, Jing

Zhu, Liangliang; Yan, Feihu; Wang, Zhen; Dong, Haiyan; Bian, Chengling; Wang, Ting; Yu, Enda; Li, Jing.

Afiliación

Zhu L; Department of Colorectal Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yan F; Department of Colorectal Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Wang Z; Department of General Surgery, The 413 Military Hospital of PLA, Zhoushan, China.
Dong H; Department of Colorectal Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Bian C; Center for Translational Medicine, Second Military Medical University, Shanghai, China.
Wang T; Department of Radiology, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yu E; Department of Genetics, Washington University School of Medicine, St. Louis, MO.
Li J; Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO.

Int J Cancer ; 143(10): 2488-2498, 2018 11 15.

Article en En | MEDLINE | ID: mdl-30183087

Asunto(s)

Neoplasias Colorrectales/genética; Metilación de ADN; Mutación; Adenoma/genética; Adenoma/patología; Estudios de Casos y Controles; Neoplasias Colorrectales/patología; Humanos

Palabras clave

DNA methylation; DNA methylation array; epimutation; laterally spreading tumors

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Metilación de ADN / Mutación Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Int J Cancer Año: 2018 Tipo del documento: Article País de afiliación: China

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