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13C-NMR-based metabolic fingerprinting of Citrus-type crude drugs.
Tsujimoto, Takashi; Yoshitomi, Taichi; Maruyama, Takuro; Yamamoto, Yutaka; Hakamatsuka, Takashi; Uchiyama, Nahoko.
Afiliación
  • Tsujimoto T; Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
  • Yoshitomi T; Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
  • Maruyama T; Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
  • Yamamoto Y; Tochimoto Tenkaido Co., Ltd., Oniya Kaibara-cho, Tamba, Hyogo 669-3315, Japan.
  • Hakamatsuka T; Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
  • Uchiyama N; Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan. Electronic address: nuchiyama@nihs.go.jp.
J Pharm Biomed Anal ; 161: 305-312, 2018 Nov 30.
Article en En | MEDLINE | ID: mdl-30193199
Five Citrus-type crude drugs (40 samples) were classified using 13C-NMR spectra-based metabolomics. The following eight metabolites were identified from the loading plots of multivariate analysis of the 13C-NMR spectra; naringin, neohesperidin, narirutin, synephrine, sucrose, α-glucose, ß-glucose, and limonene. 13C-NMR spectra-based metabolic fingerprinting is a promising strategy for classifying crude drugs.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Citrus / Fitoquímicos / Espectroscopía de Resonancia Magnética con Carbono-13 Idioma: En Revista: J Pharm Biomed Anal Año: 2018 Tipo del documento: Article País de afiliación: Japón
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Citrus / Fitoquímicos / Espectroscopía de Resonancia Magnética con Carbono-13 Idioma: En Revista: J Pharm Biomed Anal Año: 2018 Tipo del documento: Article País de afiliación: Japón