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IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos.
Fedele, Pasquale L; Willis, Simon N; Liao, Yang; Low, Michael S; Rautela, Jai; Segal, David H; Gong, Jia-Nan; Huntington, Nicholas D; Shi, Wei; Huang, David C S; Grigoriadis, George; Tellier, Julie; Nutt, Stephen L.
Afiliación
  • Fedele PL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Willis SN; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Liao Y; Haematology Department, Monash Health, Clayton, VIC, Australia.
  • Low MS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Rautela J; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Segal DH; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Gong JN; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Huntington ND; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Shi W; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Huang DCS; Haematology Department, Monash Health, Clayton, VIC, Australia.
  • Grigoriadis G; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Tellier J; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
  • Nutt SL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Blood ; 132(20): 2166-2178, 2018 11 15.
Article en En | MEDLINE | ID: mdl-30228232

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor de Transcripción Ikaros / Sistemas CRISPR-Cas / Anticuerpos Monoclonales / Mieloma Múltiple / Antineoplásicos Límite: Humans Idioma: En Revista: Blood Año: 2018 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor de Transcripción Ikaros / Sistemas CRISPR-Cas / Anticuerpos Monoclonales / Mieloma Múltiple / Antineoplásicos Límite: Humans Idioma: En Revista: Blood Año: 2018 Tipo del documento: Article País de afiliación: Australia