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The evolution of multiple active site configurations in a designed enzyme.
Hong, Nan-Sook; Petrovic, Dusan; Lee, Richmond; Gryn'ova, Ganna; Purg, Miha; Saunders, Jake; Bauer, Paul; Carr, Paul D; Lin, Ching-Yeh; Mabbitt, Peter D; Zhang, William; Altamore, Timothy; Easton, Chris; Coote, Michelle L; Kamerlin, Shina C L; Jackson, Colin J.
Afiliación
  • Hong NS; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Petrovic D; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23, Uppsala, Sweden.
  • Lee R; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Gryn'ova G; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Purg M; Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
  • Saunders J; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23, Uppsala, Sweden.
  • Bauer P; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Carr PD; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23, Uppsala, Sweden.
  • Lin CY; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Mabbitt PD; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Zhang W; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Altamore T; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Easton C; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Coote ML; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Kamerlin SCL; Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
  • Jackson CJ; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23, Uppsala, Sweden. lynn.kamerlin@kemi.uu.se.
Nat Commun ; 9(1): 3900, 2018 09 25.
Article en En | MEDLINE | ID: mdl-30254369
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diseño Asistido por Computadora / Evolución Molecular Dirigida / Dominio Catalítico / Enzimas Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diseño Asistido por Computadora / Evolución Molecular Dirigida / Dominio Catalítico / Enzimas Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Australia