A Family Focused Intervention Influences Hippocampal-Prefrontal Connectivity Through Gains in Self-Regulation.
Child Dev
; 90(4): 1389-1401, 2019 07.
Article
en En
| MEDLINE
| ID: mdl-30295319
ABSTRACT
The stressors associated with poverty increase the risks for externalizing psychopathology; however, specific patterns of neurobiology and higher self-regulation may buffer against these effects. This study leveraged a randomized control trial, aimed at increasing self-regulation at ~11 years of age. As adults, these same individuals completed functional MRI scanning (Mage = 24.88 years; intervention n = 44; control n = 49). Functional connectivity between the hippocampus and ventromedial prefrontal cortex was examined in relation to the intervention, gains in self-regulation, and present-day externalizing symptoms. Increased connectivity between these brain areas was noted in the intervention group compared to controls. Furthermore, individual gains in self-regulation, instilled by the intervention, statistically explained this brain difference. These results begin to connect neurobiological and psychosocial markers of risk and resiliency.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Síntomas Conductuales
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Conducta Infantil
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Corteza Prefrontal
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Terapia Familiar
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Conectoma
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Autocontrol
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Hipocampo
Tipo de estudio:
Clinical_trials
Límite:
Adult
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Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Child Dev
Año:
2019
Tipo del documento:
Article