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Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Hu, Carol H; Wang, Tammy C; Qiao, Jennifer X; Haque, Lauren; Chen, Alice Y A; Taylor, David S; Ying, Xiaohong; Onorato, Joelle M; Galella, Michael; Shen, Hong; Huang, Christine S; Toussaint, Nathalie; Li, Yi-Xin; Abell, Lynn; Adam, Leonard P; Gordon, David; Wexler, Ruth R; Finlay, Heather J.
Afiliación
  • Hu CH; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States. Electronic address: Carol.Hu@bms.com.
  • Wang TC; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States. Electronic address: Tammy.Wang@bms.com.
  • Qiao JX; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Haque L; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Chen AYA; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Taylor DS; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Ying X; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Onorato JM; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Galella M; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Shen H; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Huang CS; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Toussaint N; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Li YX; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Abell L; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Adam LP; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Gordon D; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Wexler RR; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
  • Finlay HJ; Research and Development, Bristol-Myers Squibb, Princeton, NJ 08543, United States.
Bioorg Med Chem Lett ; 28(23-24): 3721-3725, 2018 12 15.
Article en En | MEDLINE | ID: mdl-30348490
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinonas / Inhibidores Enzimáticos / Lipasa Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinonas / Inhibidores Enzimáticos / Lipasa Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article