In silico model-guided identification of transcriptional regulator targets for efficient strain design.

Koduru, Lokanand; Lakshmanan, Meiyappan; Lee, Dong-Yup

Koduru, Lokanand; Lakshmanan, Meiyappan; Lee, Dong-Yup.

Afiliación

Koduru L; Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore, 117576, Singapore.
Lakshmanan M; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Centros, Singapore, 138668, Singapore.
Lee DY; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Centros, Singapore, 138668, Singapore. dongyuplee@skku.edu.

Microb Cell Fact ; 17(1): 167, 2018 Oct 25.

Article en En | MEDLINE | ID: mdl-30359263

Asunto(s)

Simulación por Computador; Corynebacterium glutamicum/genética; Escherichia coli/genética; Transcripción Genética; Algoritmos; Regulación Bacteriana de la Expresión Génica; Redes Reguladoras de Genes; Genoma Bacteriano; Metaboloma

Palabras clave

Constraint-based flux analysis; Genome-scale metabolic model; Model-guided strain design; Systems biology; Transcriptional regulator

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Simulación por Computador / Corynebacterium glutamicum / Escherichia coli Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Microb Cell Fact Asunto de la revista: BIOTECNOLOGIA / MICROBIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Singapur

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