Variability in the utility of predictive models in predicting patient-reported outcomes following spine surgery for degenerative conditions: a systematic review.
Neurosurg Focus
; 45(5): E10, 2018 11 01.
Article
en En
| MEDLINE
| ID: mdl-30453453
ABSTRACT
OBJECTIVEThere is increasing emphasis on patient-reported outcomes (PROs) to quantitatively evaluate quality outcomes from degenerative spine surgery. However, accurate prediction of PROs is challenging due to heterogeneity in outcome measures, patient characteristics, treatment characteristics, and methodological characteristics. The purpose of this study was to evaluate the current landscape of independently validated predictive models for PROs in elective degenerative spinal surgery with respect to study design and model generation, training, accuracy, reliability, variance, and utility.METHODSThe authors analyzed the current predictive models in PROs by performing a search of the PubMed and Ovid databases using PRISMA guidelines and a PICOS (participants, intervention, comparison, outcomes, study design) model. They assessed the common outcomes and variables used across models as well as the study design and internal validation methods.RESULTSA total of 7 articles met the inclusion criteria, including a total of 17 validated predictive models of PROs after adult degenerative spine surgery. National registry databases were used in 4 of the studies. Validation cohorts were used in 2 studies for model verification and 5 studies used other methods, including random sample bootstrapping techniques. Reported c-index values ranged from 0.47 to 0.79. Two studies report the area under the curve (0.71-0.83) and one reports a misclassification rate (9.9%). Several positive predictors, including high baseline pain intensity and disability, demonstrated high likelihood of favorable PROs.CONCLUSIONSA limited but effective cohort of validated predictive models of spine surgical outcomes had proven good predictability for PROs. Instruments with predictive accuracy can enhance shared decision-making, improve rehabilitation, and inform best practices in the setting of heterogeneous patient characteristics and surgical factors.
Palabras clave
ASA = American Society of Anesthesiologists; AUC = area under the curve; JOABPEQ = Japanese Orthopaedic Association Back Pain Evaluation Questionnaire; LBOS = Low Back Outcome Scale; MCID = minimum clinically important difference; NRS = numeric rating scale; ODI = Oswestry Disability Index; PICOS = participants, intervention, comparison, outcomes, study design; PRO = patient-reported outcome; QOD = Quality Outcomes Database; QUADAS = Quality Assessment of Diagnostic Accuracy Studies; ROC = receiver operating characteristic; RTW = return to work; VAS = visual analog scale; degeneration; patient reported outcomes; predictive models; spine surgery
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de la Columna Vertebral
/
Modelos Estadísticos
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Medición de Resultados Informados por el Paciente
Tipo de estudio:
Guideline
/
Prognostic_studies
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Risk_factors_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Neurosurg Focus
Asunto de la revista:
NEUROCIRURGIA
Año:
2018
Tipo del documento:
Article