Curcumin improves exercise performance of mice with coronary artery ligation-induced HFrEF: Nrf2 and antioxidant mechanisms in skeletal muscle.

Wafi, Ahmed M; Hong, Juan; Rudebush, Tara L; Yu, Li; Hackfort, Bryan; Wang, Hanjun; Schultz, Harold D; Zucker, Irving H; Gao, Lie

Wafi, Ahmed M; Hong, Juan; Rudebush, Tara L; Yu, Li; Hackfort, Bryan; Wang, Hanjun; Schultz, Harold D; Zucker, Irving H; Gao, Lie.

Afiliación

Wafi AM; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Hong J; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Rudebush TL; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Yu L; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Hackfort B; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Wang H; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Schultz HD; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Zucker IH; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.
Gao L; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center , Omaha, Nebraska.

J Appl Physiol (1985) ; 126(2): 477-486, 2019 02 01.

Article en En | MEDLINE | ID: mdl-30462567

Asunto(s)

Antioxidantes/farmacología; Vasos Coronarios/cirugía; Curcumina/farmacología; Tolerancia al Ejercicio/efectos de los fármacos; Insuficiencia Cardíaca/tratamiento farmacológico; Músculo Esquelético/efectos de los fármacos; Factor 2 Relacionado con NF-E2/metabolismo; Animales; Modelos Animales de Enfermedad; Insuficiencia Cardíaca/etiología; Insuficiencia Cardíaca/metabolismo; Insuficiencia Cardíaca/fisiopatología; Hemo-Oxigenasa 1/metabolismo; Ligadura; Masculino; Proteínas de la Membrana/metabolismo; Ratones Endogámicos C57BL; Contracción Muscular/efectos de los fármacos; Fatiga Muscular/efectos de los fármacos; Fuerza Muscular/efectos de los fármacos; Músculo Esquelético/metabolismo; Músculo Esquelético/fisiopatología; Proteína MioD/metabolismo; Miogenina/metabolismo; Transducción de Señal; Superóxido Dismutasa/metabolismo; Factores de Tiempo

Palabras clave

HFrEF; exercise intolerance; myopathy; oxidative stress

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tolerancia al Ejercicio / Músculo Esquelético / Vasos Coronarios / Curcumina / Factor 2 Relacionado con NF-E2 / Insuficiencia Cardíaca / Antioxidantes Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Appl Physiol (1985) Asunto de la revista: FISIOLOGIA Año: 2019 Tipo del documento: Article

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