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Accrual to Clinical Trials (ACT): A Clinical and Translational Science Award Consortium Network.
Visweswaran, Shyam; Becich, Michael J; D'Itri, Vincent S; Sendro, Elaina R; MacFadden, Douglas; Anderson, Nicholas R; Allen, Karen A; Ranganathan, Dipti; Murphy, Shawn N; Morrato, Elaine H; Pincus, Harold A; Toto, Robert; Firestein, Gary S; Nadler, Lee M; Reis, Steven E.
Afiliación
  • Visweswaran S; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Becich MJ; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • D'Itri VS; The Chartis Group, Chicago, Illinois, USA.
  • Sendro ER; The Chartis Group, Chicago, Illinois, USA.
  • MacFadden D; The Harvard Clinical and Translational Science Center, Harvard Medical School, Boston, Massachusetts, USA.
  • Anderson NR; Department of Public Health Sciences, University of California, Davis, California, USA.
  • Allen KA; Office of Research, University of California, Irvine, California, USA.
  • Ranganathan D; Academic Information Systems, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Murphy SN; Research Computing, Partners HealthCare, Charlestown, Massachusetts, USA.
  • Morrato EH; Department of Health Systems, Management and Policy, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Pincus HA; Department of Psychiatry, Columbia University, New York, New York, USA.
  • Toto R; The Center for Translational Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Firestein GS; Altman Clinical and Translational Research Institute, University of California, San Diego, California, USA.
  • Nadler LM; The Harvard Clinical and Translational Science Center, Harvard Medical School, Boston, Massachusetts, USA.
  • Reis SE; The Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
JAMIA Open ; 1(2): 147-152, 2018 Oct.
Article en En | MEDLINE | ID: mdl-30474072
ABSTRACT
The Accrual to Clinical Trials (ACT) network is a federated network of sites from the National Clinical and Translational Science Award (CTSA) Consortium that has been created to significantly increase participant accrual to multi-site clinical trials. The ACT network represents an unprecedented collaboration among diverse CTSA sites. The network has created governance and regulatory frameworks and a common data model to harmonize electronic health record (EHR) data, and deployed a set of Informatics for Integrating Biology and the Bedside (i2b2) data repositories that are linked by the Shared Health Research Information Network (SHRINE) platform. It provides investigators the ability to query the network in real time and to obtain aggregate counts of patients who meet clinical trial inclusion and exclusion criteria from sites across the United States. The ACT network infrastructure provides a basis for cohort discovery and for developing new informatics tools to identify and recruit participants for multi-site clinical trials.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JAMIA Open Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JAMIA Open Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos