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A unique nanoparticulate TLR9 agonist enables a HA split vaccine to confer FcγR-mediated protection against heterologous lethal influenza virus infection.
Yamamoto, Takuya; Masuta, Yuji; Momota, Masatoshi; Kanekiyo, Masaru; Kanuma, Tomohiro; Takahama, Shoukichi; Moriishi, Eiko; Yasutomi, Yasuhiro; Saito, Takashi; Graham, Barney S; Takahashi, Yoshimasa; Ishii, Ken J.
Afiliación
  • Yamamoto T; Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, Osaka, Japan.
  • Masuta Y; Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan.
  • Momota M; Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, Osaka, Japan.
  • Kanekiyo M; Laboratories of Discovery Research, Nippon Shinyaku Co., Ltd., Kyoto, Japan.
  • Kanuma T; Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, Osaka, Japan.
  • Takahama S; Laboratory of Vaccine Science, World Premier International Immunology Frontier Research Center, Osaka University, Osaka, Japan.
  • Moriishi E; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Yasutomi Y; Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, Osaka, Japan.
  • Saito T; Laboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan.
  • Graham BS; Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan.
  • Takahashi Y; Laboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan.
  • Ishii KJ; Laboratory of Immunosenescence, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan.
Int Immunol ; 31(2): 81-90, 2019 02 15.
Article en En | MEDLINE | ID: mdl-30535055
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas contra la Influenza / Receptores Fc / Infecciones por Orthomyxoviridae / Gripe Humana / Nanopartículas / Hemaglutininas Virales Límite: Animals / Female / Humans Idioma: En Revista: Int Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas contra la Influenza / Receptores Fc / Infecciones por Orthomyxoviridae / Gripe Humana / Nanopartículas / Hemaglutininas Virales Límite: Animals / Female / Humans Idioma: En Revista: Int Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Japón