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18 F-FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma.
Kirchner, Julian; Schaarschmidt, Benedikt M; Sauerwein, Wolfgang; Deuschl, Cornelius; Arweiler-Harbeck, Diana; Holtmann, Laura; Stebner, Vanessa; Umutlu, Lale; Antoch, Gerald; Ruhlmann, Verena.
Afiliación
  • Kirchner J; Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  • Schaarschmidt BM; Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  • Sauerwein W; Department of Radiation Oncology, University of Duisburg-Essen, Essen, Germany.
  • Deuschl C; Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Arweiler-Harbeck D; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Holtmann L; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Stebner V; Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Umutlu L; Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Antoch G; Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  • Ruhlmann V; Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Head Neck ; 41(1): 170-176, 2019 01.
Article en En | MEDLINE | ID: mdl-30548894
ABSTRACT

OBJECTIVES:

To evaluate and compare the diagnostic potential of 18 F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18 FDG-PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC).

METHODS:

A total of 32 dedicated head and neck 18 F-FDG PET/MRI datasets were included in this analysis. MRI and 18 F-FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases.

RESULTS:

Lesion-based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for 18 F-FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of 18 F-FDG PET/MRI compared to MRI (P < .005).

CONCLUSION:

18 F-FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, 18 F-FDG PET/MRI outperforms MRI.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Carcinoma Adenoide Quístico / Tomografía de Emisión de Positrones / Neoplasias de Cabeza y Cuello / Recurrencia Local de Neoplasia Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Carcinoma Adenoide Quístico / Tomografía de Emisión de Positrones / Neoplasias de Cabeza y Cuello / Recurrencia Local de Neoplasia Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Alemania