Genetic variants in RUNX3, AMD1 and MSRA in the methionine metabolic pathway and survival in nonsmall cell lung cancer patients.

Chen, Ka; Liu, Hongliang; Liu, Zhensheng; Luo, Sheng; Patz, Edward F; Moorman, Patricia G; Su, Li; Shen, Sipeng; Christiani, David C; Wei, Qingyi

Chen, Ka; Liu, Hongliang; Liu, Zhensheng; Luo, Sheng; Patz, Edward F; Moorman, Patricia G; Su, Li; Shen, Sipeng; Christiani, David C; Wei, Qingyi.

Afiliación

Chen K; Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing, People's Republic of China.
Liu H; Duke Cancer Institute, Duke University Medical Center, Durham, NC.
Liu Z; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC.
Luo S; Duke Cancer Institute, Duke University Medical Center, Durham, NC.
Patz EF; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC.
Moorman PG; Duke Cancer Institute, Duke University Medical Center, Durham, NC.
Su L; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC.
Shen S; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC.
Christiani DC; Duke Cancer Institute, Duke University Medical Center, Durham, NC.
Wei Q; Department of Radiology, Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC.

Int J Cancer ; 145(3): 621-631, 2019 08 01.

Article en En | MEDLINE | ID: mdl-30650190

Asunto(s)

Adenosilmetionina Descarboxilasa/genética; Carcinoma de Pulmón de Células no Pequeñas/genética; Subunidad alfa 3 del Factor de Unión al Sitio Principal/genética; Neoplasias Pulmonares/genética; Metionina Sulfóxido Reductasas/genética; Metionina/metabolismo; Adenosilmetionina Descarboxilasa/metabolismo; Anciano; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/mortalidad; Subunidad alfa 3 del Factor de Unión al Sitio Principal/metabolismo; Femenino; Estudio de Asociación del Genoma Completo; Humanos; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/mortalidad; Masculino; Metionina Sulfóxido Reductasas/metabolismo; Persona de Mediana Edad; Mutación; Polimorfismo de Nucleótido Simple; Modelos de Riesgos Proporcionales; Sitios de Carácter Cuantitativo; ARN Mensajero/biosíntesis; ARN Mensajero/genética; Curva ROC; Tasa de Supervivencia

Palabras clave

genome-wide association study; methionine; nonsmall cell lung cancer; single-nucleotide polymorphism; survival

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Adenosilmetionina Descarboxilasa / Carcinoma de Pulmón de Células no Pequeñas / Metionina Sulfóxido Reductasas / Subunidad alfa 3 del Factor de Unión al Sitio Principal / Neoplasias Pulmonares / Metionina Tipo de estudio: Prognostic_studies / Systematic_reviews Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Año: 2019 Tipo del documento: Article

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