Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.

Xu, Lian; Fu, Mengxia; Chen, Dongrui; Han, Weiqing; Ostrowski, Michael C; Grossfeld, Paul; Gao, Pingjin; Ye, Maoqing

Xu, Lian; Fu, Mengxia; Chen, Dongrui; Han, Weiqing; Ostrowski, Michael C; Grossfeld, Paul; Gao, Pingjin; Ye, Maoqing.

Afiliación

Xu L; State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China.
Fu M; State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China.
Chen D; State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China.
Han W; State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China.
Ostrowski MC; Department of Cancer Biology and Genetics, The Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.
Grossfeld P; Division of Pediatric Cardiology, University of California San Diego School of Medicine, La Jolla, CA 92093, USA.
Gao P; State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China.
Ye M; State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China.

BMB Rep ; 52(10): 595-600, 2019 Oct.

Article en En | MEDLINE | ID: mdl-30670148

Asunto(s)

Transición Epitelial-Mesenquimal; Miocardio/patología; Proteína Proto-Oncogénica c-ets-1/metabolismo; Angiotensina II; Animales; Cardiomegalia/patología; Transición Epitelial-Mesenquimal/efectos de los fármacos; Transición Epitelial-Mesenquimal/genética; Fibrosis; Regulación de la Expresión Génica/efectos de los fármacos; Células HEK293; Humanos; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Proteína Proto-Oncogénica c-ets-1/genética; Transducción de Señal/efectos de los fármacos; Factor de Crecimiento Transformador beta1/farmacología; Factores de Transcripción Twist/metabolismo; Homeobox 1 de Unión a la E-Box con Dedos de Zinc/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Proto-Oncogénica c-ets-1 / Transición Epitelial-Mesenquimal / Miocardio Límite: Animals / Humans / Male Idioma: En Revista: BMB Rep Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google