A Laser Driven Flow Chemistry Platform for Scaling Photochemical Reactions with Visible Light.
ACS Cent Sci
; 5(1): 109-115, 2019 Jan 23.
Article
en En
| MEDLINE
| ID: mdl-30693330
ABSTRACT
Visible-light-promoted organic reactions can offer increased reactivity and selectivity via unique reaction pathways to address a multitude of practical synthetic problems, yet few practical solutions exist to employ these reactions for multikilogram production. We have developed a simple and versatile continuous stirred tank reactor (CSTR) equipped with a high-intensity laser to drive photochemical reactions at unprecedented rates in continuous flow, achieving kg/day throughput using a 100 mL reactor. Our approach to flow reactor design uses the Beer-Lambert law as a guideline to optimize catalyst concentration and reactor depth for maximum throughput. This laser CSTR platform coupled with the rationale for design can be applied to a breadth of photochemical reactions.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Tipo de estudio:
Guideline
Idioma:
En
Revista:
ACS Cent Sci
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos