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Evaluating metronidazole as a novel, safe CYP2A6 phenotyping probe in healthy adults.
Stancil, Stephani L; Pearce, Robin E; Tyndale, Rachel F; Kearns, Gregory L; Vyhlidal, Carrie A; Leeder, J Steven; Abdel-Rahman, Susan.
Afiliación
  • Stancil SL; Division of Adolescent Medicine, Children's Mercy Kansas City, MO, USA.
  • Pearce RE; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Kansas City, MO, USA.
  • Tyndale RF; Division of Pharmacology & Toxicology, University of Missouri-Kansas City School of Pharmacy, Kansas City, MO, USA.
  • Kearns GL; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Kansas City, MO, USA.
  • Vyhlidal CA; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, MO, USA.
  • Leeder JS; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Departments of Pharmacology & Toxicology, and Psychiatry, University of Toronto, Toronto, Ontario, Canada.
  • Abdel-Rahman S; Arkansas Children's Research Institute and the Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Br J Clin Pharmacol ; 85(5): 960-969, 2019 05.
Article en En | MEDLINE | ID: mdl-30706508
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Citocromo P-450 CYP2A6 / Pruebas de Farmacogenómica / Metronidazol / Nicotina Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Citocromo P-450 CYP2A6 / Pruebas de Farmacogenómica / Metronidazol / Nicotina Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos