Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance
Turk J Med Sci
; 49(1): 347-355, 2019 Feb 11.
Article
en En
| MEDLINE
| ID: mdl-30761849
ABSTRACT
Background/aim:
Ankaferd hemostat (ABS; Ankaferd blood stopper, Istanbul, Turkey) is a folkloric medicinal plant extract. The aim of this study was to determine the effect of Ankaferd hemostat (ABS) on the fate of Helicobacter pylori strains. The study also aims to determine alterations in the antimicrobial resistance of three different H. pylori strains in response to ABS exposure. Materials andmethods:
H. pylori Strain 1 was obtained from the culture collection ATCC 43504 and passaged three times for viability. Strain 2 was isolated from a gastric ulcer patient and Strain 3 was isolated from a gastritis patient. 1% of ABS was added to all of the strains and antimicrobial susceptibility was observed on 30 and 60 min after application.Results:
The efficacy of ABS solutions in achieving significant logarithmic reduction in foodborne pathogens of H. pylori was observed in this study. This study showed that ABS has antibacterial (Anti-H. pylori) effects.Conclusion:
Our present study indicated, for the first time, that ABS could act against H. pylori. ABS is clinically used for the management of GI bleeding due to benign and malignant GI lesions. Thus, the possible anti-H. pylori effect of ABS shall expand the therapeutic spectrum of the drug in GI lesions in relation to H. pylori infection such as peptic ulser disease (PUD) and lymphoid tissue (MALT) lymphomagenesis.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Helicobacter pylori
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Infecciones por Helicobacter
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Farmacorresistencia Bacteriana
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Enfermedades Gastrointestinales
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Antibacterianos
Límite:
Humans
Idioma:
En
Revista:
Turk J Med Sci
Año:
2019
Tipo del documento:
Article