Prolactin and alteration of fertility.

AIM: Physiology and pathology of prolactin production, clinical consequences. DESIGN: Review. SETTING: Reprogenesis International, Brno. METHODS: Study of current literature. CONCLUSION: In article is discussed physiology and pathology of prolactin production, influence of hyperprolac-tinaemia to ovarian function - anovulation, irregularities of cycle, amenorrhea. Separately is discussed problem of microprolactinoma and prolactinoma. Review of current therapeutic possibilities.