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Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours.
Serrano, César; Mariño-Enríquez, Adrián; Tao, Derrick L; Ketzer, Julia; Eilers, Grant; Zhu, Meijun; Yu, Channing; Mannan, Aristotle M; Rubin, Brian P; Demetri, George D; Raut, Chandrajit P; Presnell, Ajia; McKinley, Arin; Heinrich, Michael C; Czaplinski, Jeffrey T; Sicinska, Ewa; Bauer, Sebastian; George, Suzanne; Fletcher, Jonathan A.
Afiliación
  • Serrano C; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA. cserrano@vhio.net.
  • Mariño-Enríquez A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. cserrano@vhio.net.
  • Tao DL; Sarcoma Translational Research Laboratory, Vall d'Hebron Institute of Oncology; Department of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain. cserrano@vhio.net.
  • Ketzer J; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA.
  • Eilers G; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA.
  • Zhu M; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
  • Yu C; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA.
  • Mannan AM; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 528, Boston, MA, USA.
  • Rubin BP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Demetri GD; Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA, USA.
  • Raut CP; Daiichi Sankyo Inc., Basking Ridge, NJ, USA.
  • Presnell A; Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA, USA.
  • McKinley A; Department of Molecular Genetics, Lerner Research Institute and Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, USA.
  • Heinrich MC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Czaplinski JT; Ludwig Center for Cancer Research at Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
  • Sicinska E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bauer S; Division of Surgical Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, 75 Francis Street, Boston, MA, USA.
  • George S; Portland VA Medical Center and OHSU Knight Cancer Institute, Portland, Oregon, USA.
  • Fletcher JA; Portland VA Medical Center and OHSU Knight Cancer Institute, Portland, Oregon, USA.
Br J Cancer ; 120(6): 612-620, 2019 03.
Article en En | MEDLINE | ID: mdl-30792533
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-kit / Tumores del Estroma Gastrointestinal / Inhibidores de Proteínas Quinasas / Neoplasias Gastrointestinales / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-kit / Tumores del Estroma Gastrointestinal / Inhibidores de Proteínas Quinasas / Neoplasias Gastrointestinales / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Br J Cancer Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos