Pregnancy Outcomes in Couples with Males Exposed to Longterm Anti-tumor Necrosis Factor-α Inhibitor Therapies: A Prospective Study.
J Rheumatol
; 46(9): 1084-1088, 2019 09.
Article
en En
| MEDLINE
| ID: mdl-30824658
ABSTRACT
OBJECTIVE:
To examine the pregnancy achievement and outcomes in couples in which men with spondyloarthritis (SpA) were exposed to tumor necrosis factor inhibitors (TNFi).METHODS:
Information about pregnancies involving fathers with SpA was prospectively collected by 6 Romanian rheumatology centers.RESULTS:
Twenty-seven patients achieved 33 pregnancies and fathered 30 healthy children. Three elective abortions (personal reasons) and no spontaneous abortions, preeclampsia/eclampsia, stillbirths, congenital malformations, or pathologies in the children were recorded. Five patients showed normospermia before and after longterm TNFi treatment.CONCLUSION:
Pregnancy and child outcomes in male patients with SpA exposed to longterm TNFi therapy were reassuring.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Exposición Paterna
/
Antirreumáticos
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Espondiloartritis
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Inhibidores del Factor de Necrosis Tumoral
Tipo de estudio:
Observational_studies
Límite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
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Pregnancy
Idioma:
En
Revista:
J Rheumatol
Año:
2019
Tipo del documento:
Article