Hypoxia-inducible factor-1&#945; and nuclear factor-&#954;B play important roles in regulating programmed cell death ligand 1 expression by epidermal growth factor receptor mutants in non-small-cell lung cancer cells.

Guo, Rong; Li, Yong; Wang, Zhijie; Bai, Hua; Duan, Jianchun; Wang, Shuhang; Wang, Lvhua; Wang, Jie

Hypoxia-inducible factor-1α and nuclear factor-κB play important roles in regulating programmed cell death ligand 1 expression by epidermal growth factor receptor mutants in non-small-cell lung cancer cells.

Guo, Rong; Li, Yong; Wang, Zhijie; Bai, Hua; Duan, Jianchun; Wang, Shuhang; Wang, Lvhua; Wang, Jie.

Afiliación

Guo R; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Li Y; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Laboratory Animal, Peking University Cancer Hospital and Institute, Beijing, China.
Wang Z; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Bai H; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Duan J; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Wang S; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Wang L; Department of Radiation Therapy, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Wang J; Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

Cancer Sci ; 110(5): 1665-1675, 2019 May.

Article en En | MEDLINE | ID: mdl-30844110

Asunto(s)

Antígeno B7-H1/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/patología; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo; Neoplasias Pulmonares/patología; FN-kappa B/metabolismo; Animales; Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Línea Celular Tumoral; Receptores ErbB/genética; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Sistema de Señalización de MAP Quinasas; Masculino; Ratones Desnudos; Mutación; Fosforilación; Trasplante Heterólogo

Palabras clave

Hypoxia-inducible factor-1α; NF-κB; epidermal growth factor receptor; non-small-cell lung cancer; programmed cell death ligand 1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: FN-kappa B / Carcinoma de Pulmón de Células no Pequeñas / Subunidad alfa del Factor 1 Inducible por Hipoxia / Antígeno B7-H1 / Neoplasias Pulmonares Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Sci Año: 2019 Tipo del documento: Article País de afiliación: China

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