The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency.

Manczyk, Noah; Veggiani, Gianluca; Teyra, Joan; Strilchuk, Amy W; Sidhu, Sachdev S; Sicheri, Frank

Manczyk, Noah; Veggiani, Gianluca; Teyra, Joan; Strilchuk, Amy W; Sidhu, Sachdev S; Sicheri, Frank.

Afiliación

Manczyk N; Department of Biochemistry, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Veggiani G; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.
Teyra J; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Strilchuk AW; Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
Sidhu SS; Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
Sicheri F; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.

Sci Rep ; 9(1): 4119, 2019 03 11.

Article en En | MEDLINE | ID: mdl-30858488

Asunto(s)

Dominio Catalítico; Endopeptidasas/química; Animales; Endopeptidasas/genética; Endopeptidasas/metabolismo; Humanos; Mutación; Unión Proteica; Ubiquitinas/química; Ubiquitinas/metabolismo; Pez Cebra

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Dominio Catalítico Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Canadá

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