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Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.
Eyre, David W; Town, Katy; Street, Teresa; Barker, Leanne; Sanderson, Nicholas; Cole, Michelle J; Mohammed, Hamish; Pitt, Rachel; Gobin, Maya; Irish, Charles; Gardiner, Daniel; Sedgwick, James; Beck, Charles; Saunders, John; Turbitt, Deborah; Cook, Clare; Phin, Nick; Nathan, Bavithra; Horner, Paddy; Fifer, Helen.
Afiliación
  • Eyre DW; Big Data Institute, University of Oxford, Oxford, United Kingdom.
  • Town K; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Street T; National Incident Management Team, Public Health England, London, United Kingdom.
  • Barker L; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Sanderson N; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Cole MJ; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Mohammed H; National Incident Management Team, Public Health England, London, United Kingdom.
  • Pitt R; National Incident Management Team, Public Health England, London, United Kingdom.
  • Gobin M; National Incident Management Team, Public Health England, London, United Kingdom.
  • Irish C; National Incident Management Team, Public Health England, London, United Kingdom.
  • Gardiner D; National Incident Management Team, Public Health England, London, United Kingdom.
  • Sedgwick J; National Incident Management Team, Public Health England, London, United Kingdom.
  • Beck C; National Incident Management Team, Public Health England, London, United Kingdom.
  • Saunders J; National Incident Management Team, Public Health England, London, United Kingdom.
  • Turbitt D; National Incident Management Team, Public Health England, London, United Kingdom.
  • Cook C; National Incident Management Team, Public Health England, London, United Kingdom.
  • Phin N; National Incident Management Team, Public Health England, London, United Kingdom.
  • Nathan B; National Incident Management Team, Public Health England, London, United Kingdom.
  • Horner P; National Incident Management Team, Public Health England, London, United Kingdom.
  • Fifer H; These authors contributed equally to this work.
Euro Surveill ; 24(10)2019 Mar.
Article en En | MEDLINE | ID: mdl-30862336
ABSTRACT
We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ceftriaxona / Gonorrea / Azitromicina / Farmacorresistencia Bacteriana / Ertapenem / Antibacterianos / Neisseria gonorrhoeae Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans País/Región como asunto: Europa Idioma: En Revista: Euro Surveill Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ceftriaxona / Gonorrea / Azitromicina / Farmacorresistencia Bacteriana / Ertapenem / Antibacterianos / Neisseria gonorrhoeae Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans País/Región como asunto: Europa Idioma: En Revista: Euro Surveill Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido