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Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion-Driven Cancer.
Slotkin, Emily K; Diolaiti, Daniel; Shukla, Neerav N; Dela Cruz, Filemon S; Clark, Jennifer J; Gundem, Gunes; Yellapantula, Venkata D; Levine, Max F; You, Daoqi; Ma, Peilin; Pachhal, Sagarika; Ibanez Sanchez, Glorymar; Benayed, Ryma; Jungbluth, Achim A; Smyth, Lillian M; Mauguen, Audrey; Gushterova, Irena; Ding, Hongxu; Spraggon, Lee; Darnell, Robert; Califano, Andrea; Ladanyi, Marc; Papaemmanuil, Elli; Kung, Andrew L; Hyman, David M; Roberts, Stephen S.
Afiliación
  • Slotkin EK; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York. slotkine@mskcc.org.
  • Diolaiti D; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Shukla NN; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Dela Cruz FS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Clark JJ; Rocky Mountain Hospital for Children, Denver, Colorado.
  • Gundem G; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Yellapantula VD; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Levine MF; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • You D; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ma P; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Pachhal S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ibanez Sanchez G; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Benayed R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Jungbluth AA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Smyth LM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Mauguen A; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Gushterova I; Columbia University Medical Center, New York, New York.
  • Ding H; Columbia University Medical Center, New York, New York.
  • Spraggon L; Oxford Genetics, Oxford, United Kingdom.
  • Darnell R; New York Genome Center, New York, New York.
  • Califano A; Columbia University Medical Center, New York, New York.
  • Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Papaemmanuil E; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Kung AL; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Hyman DM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Roberts SS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Cancer Discov ; 9(5): 605-616, 2019 05.
Article en En | MEDLINE | ID: mdl-30877085

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-akt Tipo de estudio: Prognostic_studies Límite: Animals / Child / Female / Humans Idioma: En Revista: Cancer Discov Año: 2019 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-akt Tipo de estudio: Prognostic_studies Límite: Animals / Child / Female / Humans Idioma: En Revista: Cancer Discov Año: 2019 Tipo del documento: Article