S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2.

Liu, Lili; Qi, Lei; Knifley, Teresa; Piecoro, Dava W; Rychahou, Piotr; Liu, Jinpeng; Mitov, Mihail I; Martin, Jeremiah; Wang, Chi; Wu, Jianrong; Weiss, Heidi L; Butterfield, D Allan; Evers, B Mark; O'Connor, Kathleen L; Chen, Min

Liu, Lili; Qi, Lei; Knifley, Teresa; Piecoro, Dava W; Rychahou, Piotr; Liu, Jinpeng; Mitov, Mihail I; Martin, Jeremiah; Wang, Chi; Wu, Jianrong; Weiss, Heidi L; Butterfield, D Allan; Evers, B Mark; O'Connor, Kathleen L; Chen, Min.

Afiliación

Liu L; From the Markey Cancer Center and.
Qi L; From the Markey Cancer Center and.
Knifley T; From the Markey Cancer Center and.
Piecoro DW; the Departments of Pathology and Laboratory Medicine.
Rychahou P; From the Markey Cancer Center and.
Liu J; Surgery.
Mitov MI; From the Markey Cancer Center and.
Martin J; Biostatistics.
Wang C; From the Markey Cancer Center and.
Wu J; From the Markey Cancer Center and.
Weiss HL; Surgery.
Butterfield DA; From the Markey Cancer Center and.
Evers BM; Biostatistics.
O'Connor KL; From the Markey Cancer Center and.
Chen M; Biostatistics.

J Biol Chem ; 294(18): 7516-7527, 2019 05 03.

Article en En | MEDLINE | ID: mdl-30885944

Asunto(s)

Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patología; NADH Deshidrogenasa/metabolismo; Invasividad Neoplásica; Proteína de Unión al Calcio S100A4/metabolismo; Regulación hacia Arriba; Adenosina Trifosfato/biosíntesis; Línea Celular Tumoral; Silenciador del Gen; Glucólisis; Humanos; NADH Deshidrogenasa/genética; Metástasis de la Neoplasia; Transducción de Señal

Palabras clave

NADH:ubiquinone oxidoreductase core subunit S2 (NDUFS2); S100 calcium-binding protein A4 (S100A4); S100 proteins; cellular respiration; energy metabolism; fibroblast-specific protein-1; glycolysis; invasion; lung cancer; metastasin-1; metastasis; mitochondria; mitochondrial complex I; mitochondrial respiratory chain complex; non-small cell lung cancer (NSCLC)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación hacia Arriba / Proteína de Unión al Calcio S100A4 / Neoplasias Pulmonares / NADH Deshidrogenasa / Invasividad Neoplásica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article

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