Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling.

Hu, Chunyan; Liu, Yun; Teng, Mengying; Jiao, Kailin; Zhen, Jing; Wu, Maoxuan; Li, Zhong

Hu, Chunyan; Liu, Yun; Teng, Mengying; Jiao, Kailin; Zhen, Jing; Wu, Maoxuan; Li, Zhong.

Afiliación

Hu C; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Liu Y; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Teng M; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Jiao K; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Zhen J; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Wu M; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China.
Li Z; Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, China. lz-ny@njmu.edu.cn.

Cell Biol Toxicol ; 35(5): 445-456, 2019 10.

Article en En | MEDLINE | ID: mdl-30941654

Asunto(s)

Neoplasias de la Mama/metabolismo; Proteína Potenciadora del Homólogo Zeste 2/metabolismo; Resveratrol/uso terapéutico; Butadienos/farmacología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Receptor alfa de Estrógeno/metabolismo; Estrógenos/metabolismo; Femenino; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Humanos; Sistema de Señalización de MAP Quinasas/efectos de los fármacos; Proteína Quinasa 3 Activada por Mitógenos/metabolismo; Nitrilos/farmacología; Fosforilación/efectos de los fármacos; Resveratrol/metabolismo; Transducción de Señal/efectos de los fármacos

Palabras clave

EZH2; Estrogen receptor; Phospho-ERK1/2; Proliferation; Resveratrol

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Proteína Potenciadora del Homólogo Zeste 2 / Resveratrol Límite: Female / Humans Idioma: En Revista: Cell Biol Toxicol Asunto de la revista: TOXICOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China

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