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Cardiomyocyte PKA Ablation Enhances Basal Contractility While Eliminates Cardiac ß-Adrenergic Response Without Adverse Effects on the Heart.
Zhang, Ying; Wang, Wei Eric; Zhang, Xiaoying; Li, Ying; Chen, Biyi; Liu, Chong; Ai, Xiaojie; Zhang, Xiaoxiao; Tian, Ying; Zhang, Chen; Tang, Mingxin; Szeto, Christopher; Hua, Xiang; Xie, Mingxin; Zeng, Chunyu; Wu, Yingjie; Zhou, Lin; Zhu, Weizhong; Yu, Daohai; Houser, Steven R; Chen, Xiongwen.
Afiliación
  • Zhang Y; Cardiology, Daping Hospital, Third Military Medical University, Chongqing (Y.Z., W.E.W., C. Zeng, L.Z.).
  • Wang WE; Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University (Y.Z.).
  • Zhang X; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Li Y; Cardiology, Daping Hospital, Third Military Medical University, Chongqing (Y.Z., W.E.W., C. Zeng, L.Z.).
  • Chen B; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Liu C; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Ai X; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Zhang X; The General Hospital of The PLA Rocket Force, Beijing, China (Y.L.).
  • Tian Y; Division of Cardiovascular Medicine, Department of Internal Medicine, François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine (B.C.).
  • Zhang C; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Tang M; Pharmacology, Second Military Medical University, Shanghai (C.L.).
  • Szeto C; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Hua X; School of Agriculture and Biology, Shanghai Key Laboratory of Veterinary Biotechnology, Shanghai Jiao Tong University (X.A.).
  • Xie M; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Zeng C; Department of Ultrasound, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan (X.Z., M.X.).
  • Wu Y; Department of Pharmacology, Center for Translational Medicine (Y.T., W.Z.), Temple University School of Medicine, Philadelphia, PA.
  • Zhou L; Cardiology, Daping Hospital, Third Military Medical University, Chongqing (Y.Z., W.E.W., C. Zeng, L.Z.).
  • Zhu W; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Yu D; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Houser SR; Department of Physiology and Cardiovascular Research Center (Y.Z., W.E.W., X.Z., Y.L., C.L., X.A., X.Z., C.Z., M.T., C.S., S.R.H., X.C.), Temple University School of Medicine, Philadelphia, PA.
  • Chen X; Fox Chase Cancer Center, Philadelphia, PA (X.H.).
Circ Res ; 124(12): 1760-1777, 2019 06 07.
Article en En | MEDLINE | ID: mdl-30982412
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Adrenérgicos beta / Proteínas Quinasas Dependientes de AMP Cíclico / Miocitos Cardíacos / Inhibidores de Proteínas Quinasas / Contracción Miocárdica Límite: Animals Idioma: En Revista: Circ Res Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Adrenérgicos beta / Proteínas Quinasas Dependientes de AMP Cíclico / Miocitos Cardíacos / Inhibidores de Proteínas Quinasas / Contracción Miocárdica Límite: Animals Idioma: En Revista: Circ Res Año: 2019 Tipo del documento: Article