Aberrant DNA methylation as a diagnostic biomarker of diabetic embryopathy.

Schulze, Katharina V; Bhatt, Amit; Azamian, Mahshid S; Sundgren, Nathan C; Zapata, Gladys E; Hernandez, Patricia; Fox, Karin; Kaiser, Jeffrey R; Belmont, John W; Hanchard, Neil A

Schulze, Katharina V; Bhatt, Amit; Azamian, Mahshid S; Sundgren, Nathan C; Zapata, Gladys E; Hernandez, Patricia; Fox, Karin; Kaiser, Jeffrey R; Belmont, John W; Hanchard, Neil A.

Afiliación

Schulze KV; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Bhatt A; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Azamian MS; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Sundgren NC; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Zapata GE; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Hernandez P; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Fox K; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Kaiser JR; Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA.
Belmont JW; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Hanchard NA; Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA.

Genet Med ; 21(11): 2453-2461, 2019 11.

Article en En | MEDLINE | ID: mdl-30992551

Asunto(s)

Metilación de ADN/genética; Diabetes Mellitus/embriología; Enfermedades Fetales/genética; Alelos; Biomarcadores; Islas de CpG/genética; Complicaciones de la Diabetes/genética; Diabetes Mellitus/genética; Femenino; Estudio de Asociación del Genoma Completo; Humanos; Lactante; Recién Nacido; Polimorfismo de Nucleótido Simple/genética; Embarazo; Sitios de Carácter Cuantitativo/genética

Palabras clave

allele-specific methylation; bisulfite sequencing; diabetic embryopathy; infant of a diabetic mother; teratogens

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Metilación de ADN / Diabetes Mellitus / Enfermedades Fetales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Infant / Newborn / Pregnancy Idioma: En Revista: Genet Med Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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