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Novel C-2 Symmetric Molecules as α-Glucosidase and α-Amylase Inhibitors: Design, Synthesis, Kinetic Evaluation, Molecular Docking and Pharmacokinetics.
Shahzad, Danish; Saeed, Aamer; Larik, Fayaz Ali; Channar, Pervaiz Ali; Abbas, Qamar; Alajmi, Mohamed F; Arshad, M Ifzan; Erben, Mauricio F; Hassan, Mubashir; Raza, Hussain; Seo, Sung-Yum; El-Seedi, Hesham R.
Afiliación
  • Shahzad D; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. danish.scientist.shahzad@gmail.com.
  • Saeed A; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. aamersaeed@yahoo.com.
  • Larik FA; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. fayazali@chem.qau.edu.pk.
  • Channar PA; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. mrpervaiz@gmail.com.
  • Abbas Q; Department of Physiology, University of Sindh, Jamshoro 76080, Pakistan. qamar.abbas.qau@gmail.com.
  • Alajmi MF; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. malajmii@ksu.edu.sa.
  • Arshad MI; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. ifzan_ifzan@yahoo.com.
  • Erben MF; CEQUINOR (UNLP, CONICET-CCT La Plata), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Boulevard 120 e/60 y 64 N°1465, La Plata 1900, Argentina. erbenmf@gmail.com.
  • Hassan M; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 32588, Korea. mubashirhassan_gcul@yahoo.com.
  • Raza H; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 32588, Korea. hussain_solangi@yahoo.com.
  • Seo SY; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 32588, Korea. dnalove@kongju.ac.kr.
  • El-Seedi HR; Pharmacognosy Group, Department of Medicinal Chemistry, Biomedical Center (BMC), Uppsala University, SE-751 23 Uppsala, Sweden. Hesham.El-Seedi@fkog.uu.se.
Molecules ; 24(8)2019 Apr 17.
Article en En | MEDLINE | ID: mdl-30999646
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Alfa-Amilasas / Alfa-Glucosidasas / Simulación del Acoplamiento Molecular / Inhibidores de Glicósido Hidrolasas Tipo de estudio: Evaluation_studies Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Pakistán
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Alfa-Amilasas / Alfa-Glucosidasas / Simulación del Acoplamiento Molecular / Inhibidores de Glicósido Hidrolasas Tipo de estudio: Evaluation_studies Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Pakistán