Ultrasound assessment of gastric emptying time in preterm infants: A prospective observational study.
Eur J Anaesthesiol
; 36(6): 406-410, 2019 06.
Article
en En
| MEDLINE
| ID: mdl-31021881
ABSTRACT
BACKGROUND:
In paediatric anaesthesia, pre-operative fasting should be short to prevent discomfort, hunger, thirst and metabolic disorders. Current European guidelines recommend pre-operative fasting times of 4âh for breast milk and 6âh for formula milk in infants, whereas some national guidelines allow both until 4âh before anaesthesia.OBJECTIVE:
We evaluated the gastric emptying times of preterm infants after breast milk and formula milk, hypothesising that the mean gastric emptying time would be less than 4âh.DESIGN:
A prospective, observational, noninterventional cohort study.SETTING:
Neonatal ICU of a university hospital from August to September 2017. PATIENTS Twenty-two infants with a postmenstrual meanâ±âSD (range) age of 35â±â2 (32 to 40) weeks were included. Based on their prescription plan, 10 infants received breast milk and 12 received formula milk with a total volume of 50â±â16 (24 to 70)âml.INTERVENTIONS:
Gastric emptying was examined by sonographic measurements of the gastric antral area (GAA) before (FT0) and hourly after breast milk or formula milk feeding (FT1 to FT3). MAIN OUTCOMEMEASURES:
Estimated gastric emptying time after enteral feeding with breast milk and formula milk in preterm infants.RESULTS:
The GAA of the preterm infants initially increased and subsequently decreased after feeding. GAA correlated significantly with fasting time (râ=â-0.53, Pâ<â0.0001). At FT3 [199â±â16 (175 to 225)âmin], GAA was 0.57 (0.42 to 0.91)âcm and showed no difference compared with FT0. Using a linear regression model, the calculated mean gastric emptying time was 218âmin.CONCLUSION:
The study shows that the mean gastric emptying time after enteral feeding with breast milk and formula milk is less than 4âh in preterm infants. These results support our current national fasting regimen of 4âh for any milk composition in infants before anaesthesia. TRIAL REGISTRATION German registry of clinical studies (DRKS-ID DRKS 00013893).
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Estómago
/
Recien Nacido Prematuro
/
Nutrición Enteral
/
Vaciamiento Gástrico
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
Límite:
Humans
/
Newborn
Idioma:
En
Revista:
Eur J Anaesthesiol
Asunto de la revista:
ANESTESIOLOGIA
Año:
2019
Tipo del documento:
Article