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Genes with High Network Connectivity Are Enriched for Disease Heritability.
Kim, Samuel S; Dai, Chengzhen; Hormozdiari, Farhad; van de Geijn, Bryce; Gazal, Steven; Park, Yongjin; O'Connor, Luke; Amariuta, Tiffany; Loh, Po-Ru; Finucane, Hilary; Raychaudhuri, Soumya; Price, Alkes L.
Afiliación
  • Kim SS; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address: sungil@mit.edu.
  • Dai C; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Hormozdiari F; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  • van de Geijn B; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  • Gazal S; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  • Park Y; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • O'Connor L; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA 02138, USA.
  • Amariuta T; Program in Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA 02138, USA.
  • Loh PR; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Finucane H; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Raychaudhuri S; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Price AL; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Elect
Am J Hum Genet ; 104(5): 896-913, 2019 05 02.
Article en En | MEDLINE | ID: mdl-31051114
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biología Computacional / Carácter Cuantitativo Heredable / Herencia Multifactorial / Polimorfismo de Nucleótido Simple / Redes Reguladoras de Genes / Genes / Enfermedades Genéticas Congénitas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biología Computacional / Carácter Cuantitativo Heredable / Herencia Multifactorial / Polimorfismo de Nucleótido Simple / Redes Reguladoras de Genes / Genes / Enfermedades Genéticas Congénitas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2019 Tipo del documento: Article