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Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.
Qian, Hongwu; Cao, Pingping; Hu, Miaohui; Gao, Shuai; Yan, Nieng; Gong, Xin.
Afiliación
  • Qian H; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA.
  • Cao P; State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences and School of Medicine, Tsinghua University, Beijing, 100084, China.
  • Hu M; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA.
  • Gao S; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA.
  • Yan N; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA. nyan@princeton.edu.
  • Gong X; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA. gongx@sustech.edu.cn.
Nat Commun ; 10(1): 2320, 2019 05 24.
Article en En | MEDLINE | ID: mdl-31127104

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Hedgehog / Receptor Patched-1 / Dominios Proteicos Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Hedgehog / Receptor Patched-1 / Dominios Proteicos Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos