Contributions of Lorente de Nó to the Nonlinear Circuitry of the Brain.

ABSTRACT

Rafael Lorente de Nó, the youngest disciple of Santiago Ramón y Cajal, made significant and versatile contributions to the broad area of neuroscience. Present assay highlights the groundbreaking contributions of this Spanish investigator to neuronal connectivity. From Lorente de Nó laws of plurality and recurrence of connections among neurons emerged nonlinear connectivity and, therefore, set the foundation to understand the emergent properties of neuronal circuits. The emergence, truthfulness, and applicability of these organizing principles are discussed in the context of their current impact in studying neuronal ensembles. Anat Rec, 3031215-1220, 2020. © 2019 American Association for Anatomy.