Orthogonal Drug Pooling Enhances Phenotype-Based Discovery of Ocular Antiangiogenic Drugs in Zebrafish Larvae.

Ohnesorge, Nils; Sasore, Temitope; Hillary, Daniel; Alvarez, Yolanda; Carey, Michelle; Kennedy, Breandán N

Ohnesorge, Nils; Sasore, Temitope; Hillary, Daniel; Alvarez, Yolanda; Carey, Michelle; Kennedy, Breandán N.

Afiliación

Ohnesorge N; UCD School of Biomolecular and Biomedical Sciences, and UCD Conway Institute, University College Dublin, Dublin, Ireland.
Sasore T; UCD School of Biomolecular and Biomedical Sciences, and UCD Conway Institute, University College Dublin, Dublin, Ireland.
Hillary D; School of Mathematics & Statistics, University College Dublin, Dublin, Ireland.
Alvarez Y; UCD School of Biomolecular and Biomedical Sciences, and UCD Conway Institute, University College Dublin, Dublin, Ireland.
Carey M; School of Mathematics & Statistics, University College Dublin, Dublin, Ireland.
Kennedy BN; UCD School of Biomolecular and Biomedical Sciences, and UCD Conway Institute, University College Dublin, Dublin, Ireland.

Front Pharmacol ; 10: 508, 2019.

Article en En | MEDLINE | ID: mdl-31178719

Palabras clave

3R; Zebrafish; angiogenesis; drug pooling; eye vascular system; library screening; orthogonal pooling strategy; self-deconvoluting matrix

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Front Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Irlanda

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