Anti-inflammatory Trained Immunity Mediated by Helminth Products Attenuates the Induction of T Cell-Mediated Autoimmune Disease.

Quinn, Shauna M; Cunningham, Kyle; Raverdeau, Mathilde; Walsh, Robert J; Curham, Lucy; Malara, Anna; Mills, Kingston H G

Quinn, Shauna M; Cunningham, Kyle; Raverdeau, Mathilde; Walsh, Robert J; Curham, Lucy; Malara, Anna; Mills, Kingston H G.

Afiliación

Quinn SM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Cunningham K; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Raverdeau M; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Walsh RJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Curham L; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Malara A; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Mills KHG; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Front Immunol ; 10: 1109, 2019.

Article en En | MEDLINE | ID: mdl-31178861

Asunto(s)

Inmunidad Adaptativa; Antígenos Helmínticos/inmunología; Enfermedades Autoinmunes/etiología; Enfermedades Autoinmunes/metabolismo; Autoinmunidad; Linfocitos T/inmunología; Linfocitos T/metabolismo; Animales; Enfermedades Autoinmunes/patología; Modelos Animales de Enfermedad; Encefalomielitis Autoinmune Experimental; Histonas/metabolismo; Inmunidad Innata; Memoria Inmunológica; Lipopolisacáridos/inmunología; Activación de Linfocitos/inmunología; Macrófagos/inmunología; Macrófagos/metabolismo; Ratones; Monocitos/inmunología; Monocitos/metabolismo; Neutrófilos/inmunología; Neutrófilos/metabolismo

Palabras clave

EAE; Th17 cells; autoimmune disease; helminth parasite; innate immune memory; macrophages; trained immunity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Linfocitos T / Autoinmunidad / Inmunidad Adaptativa / Antígenos Helmínticos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Immunol Año: 2019 Tipo del documento: Article País de afiliación: Irlanda

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