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Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Sharif, Humayun; Wang, Li; Wang, Wei Li; Magupalli, Venkat Giri; Andreeva, Liudmila; Qiao, Qi; Hauenstein, Arthur V; Wu, Zhaolong; Núñez, Gabriel; Mao, Youdong; Wu, Hao.
Afiliación
  • Sharif H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Wang L; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Wang WL; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Magupalli VG; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Andreeva L; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Qiao Q; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Hauenstein AV; State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, China.
  • Wu Z; Center for Quantitative Biology, Peking University, Beijing, China.
  • Núñez G; Intel Parallel Computing Center for Structural Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Mao Y; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wu H; Department of Microbiology, Harvard Medical School, Boston, MA, USA.
Nature ; 570(7761): 338-343, 2019 06.
Article en En | MEDLINE | ID: mdl-31189953
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microscopía por Crioelectrón / Inflamasomas / Quinasas Relacionadas con NIMA / Proteína con Dominio Pirina 3 de la Familia NLR Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nature Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microscopía por Crioelectrón / Inflamasomas / Quinasas Relacionadas con NIMA / Proteína con Dominio Pirina 3 de la Familia NLR Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nature Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos