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Immune Reconstitution Inflammatory Syndrome as a Posttransplantation Complication in Primary Immunodeficiency With Disseminated Mycobacterium avium.
Manion, Maura; Dimitrova, Dimana; Pei, Luxin; Gea-Banacloche, Juan; Zelazny, Adrian; Lisco, Andrea; Zerbe, Christa; Freeman, Alexandra F; Holland, Steven M; Kanakry, Christopher G; Kanakry, Jennifer A; Sereti, Irini.
Afiliación
  • Manion M; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
  • Dimitrova D; National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Pei L; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
  • Gea-Banacloche J; Mayo Clinic, Phoenix, Arizona.
  • Zelazny A; Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland.
  • Lisco A; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
  • Zerbe C; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
  • Freeman AF; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
  • Holland SM; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
  • Kanakry CG; National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Kanakry JA; National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Sereti I; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Clin Infect Dis ; 70(4): 676-679, 2020 02 03.
Article en En | MEDLINE | ID: mdl-31190050
ABSTRACT
Patients with primary immunodeficiencies undergoing allogeneic hematopoietic cell transplantation (HCT) for difficult-to-control infections can experience immune reconstitution inflammatory syndrome (IRIS) following engraftment. In 3 patients with post-HCT IRIS related to mycobacterial infection, in vitro data demonstrate the emergence of pathogen-specific immune responses and a concomitant rise in plasma inflammatory markers.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Células Madre Hematopoyéticas / Síndrome Inflamatorio de Reconstitución Inmune / Enfermedades de Inmunodeficiencia Primaria / Infecciones por Mycobacterium Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2020 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Células Madre Hematopoyéticas / Síndrome Inflamatorio de Reconstitución Inmune / Enfermedades de Inmunodeficiencia Primaria / Infecciones por Mycobacterium Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2020 Tipo del documento: Article