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Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis.
Wang, Jingxiao; Wang, Haichuan; Peters, Michele; Ding, Ning; Ribback, Silvia; Utpatel, Kirsten; Cigliano, Antonio; Dombrowski, Frank; Xu, Meng; Chen, Xinyan; Song, Xinhua; Che, Li; Evert, Matthias; Cossu, Antonio; Gordan, John; Zeng, Yong; Chen, Xin; Calvisi, Diego F.
Afiliación
  • Wang J; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States.
  • Wang H; Department of Liver Surgery, Liver Transplantation Division, West China Hospital, Sichuan University, Chengdu, China; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States; Laboratory of Liver Surgery, West China Hospital,
  • Peters M; Institute of Pathology, University of Greifswald, Greifswald, Germany.
  • Ding N; Department of Gastroenterology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
  • Ribback S; Institute of Pathology, University of Greifswald, Greifswald, Germany.
  • Utpatel K; Institute of Pathology, University of Regensburg, Regensburg, Germany.
  • Cigliano A; Institute of Pathology, University of Greifswald, Greifswald, Germany; Institute of Pathology, University of Regensburg, Regensburg, Germany.
  • Dombrowski F; Institute of Pathology, University of Greifswald, Greifswald, Germany.
  • Xu M; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States; Department of General Surgery, The Second Hospital of Xi'an Jiaotong University, Xi'an Jiaotong University, Xi'an, China.
  • Chen X; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States; Department of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
  • Song X; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States.
  • Che L; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States.
  • Evert M; Institute of Pathology, University of Regensburg, Regensburg, Germany.
  • Cossu A; Unit of Pathology, Azienda Ospedaliero Universitaria Sassari, Sassari, Italy.
  • Gordan J; Department of Medicine, University of California, San Francisco, CA, United States.
  • Zeng Y; Department of Liver Surgery, Liver Transplantation Division, West China Hospital, Sichuan University, Chengdu, China; Laboratory of Liver Surgery, West China Hospital, Sichuan University, Chengdu, China. Electronic address: zengyong@medmail.com.cn.
  • Chen X; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, United States. Electronic address: xin.chen@ucsf.edu.
  • Calvisi DF; Institute of Pathology, University of Greifswald, Greifswald, Germany; Institute of Pathology, University of Regensburg, Regensburg, Germany. Electronic address: diego.calvisi@klinik.uni-regensburg.de.
J Hepatol ; 71(4): 742-752, 2019 10.
Article en En | MEDLINE | ID: mdl-31195063
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-myc / Colangiocarcinoma / Proteínas de Ciclo Celular / Proteínas Adaptadoras Transductoras de Señales / Receptor Notch2 / Carcinogénesis / Proteína 7 que Contiene Repeticiones F-Box-WD / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-myc / Colangiocarcinoma / Proteínas de Ciclo Celular / Proteínas Adaptadoras Transductoras de Señales / Receptor Notch2 / Carcinogénesis / Proteína 7 que Contiene Repeticiones F-Box-WD / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos