2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes injury-induced vascular neointima formation in mice.

Guo, Shumin; Zhang, Rui; Liu, Qian; Wan, Qiangyou; Wang, Yuanyang; Yu, Yu; Liu, Guizhu; Shen, Yujun; Yu, Ying; Zhang, Jian

Guo, Shumin; Zhang, Rui; Liu, Qian; Wan, Qiangyou; Wang, Yuanyang; Yu, Yu; Liu, Guizhu; Shen, Yujun; Yu, Ying; Zhang, Jian.

Afiliación

Guo S; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhang R; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Liu Q; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Wan Q; CAS Key Laboratory of Nutrition, Metabolism, and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Wang Y; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yu Y; Department of Pediatric Cardiovascular, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Liu G; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Shen Y; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yu Y; Department of Pharmacology and Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhang J; CAS Key Laboratory of Nutrition, Metabolism, and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.

FASEB J ; 33(9): 10207-10217, 2019 09.

Article en En | MEDLINE | ID: mdl-31216422

Asunto(s)

Endotelio Vascular/lesiones; Contaminantes Ambientales/toxicidad; Neointima/inducido químicamente; Dibenzodioxinas Policloradas/toxicidad; Animales; Aorta/citología; Ciclo Celular/efectos de los fármacos; Endotelio Vascular/efectos de los fármacos; Arteria Femoral/efectos de los fármacos; Arteria Femoral/lesiones; Regulación de la Expresión Génica/efectos de los fármacos; Técnicas de Inactivación de Genes; Genes Reporteros; Genes jun; Humanos; Hiperplasia; Masculino; Ratones; Ratones Endogámicos C57BL; Miocitos del Músculo Liso/efectos de los fármacos; Miocitos del Músculo Liso/metabolismo; Neointima/etiología; Fenotipo; Proteínas Proto-Oncogénicas c-jun/biosíntesis; Proteínas Proto-Oncogénicas c-jun/genética; Interferencia de ARN; ARN Mensajero/biosíntesis; ARN Mensajero/genética; ARN Interferente Pequeño/genética; ARN Interferente Pequeño/farmacología; Receptores de Hidrocarburo de Aril/antagonistas & inhibidores; Receptores de Hidrocarburo de Aril/genética; Receptores de Hidrocarburo de Aril/fisiología; Remodelación Vascular/efectos de los fármacos

Palabras clave

neointima formation; proliferation; vascular smooth muscle cells

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endotelio Vascular / Contaminantes Ambientales / Neointima / Dibenzodioxinas Policloradas Tipo de estudio: Etiology_studies Límite: Animals / Humans / Male Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China

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