Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer.

Jager, Myrthe; Blokzijl, Francis; Kuijk, Ewart; Bertl, Johanna; Vougioukalaki, Maria; Janssen, Roel; Besselink, Nicolle; Boymans, Sander; de Ligt, Joep; Pedersen, Jakob Skou; Hoeijmakers, Jan; Pothof, Joris; van Boxtel, Ruben; Cuppen, Edwin

Jager, Myrthe; Blokzijl, Francis; Kuijk, Ewart; Bertl, Johanna; Vougioukalaki, Maria; Janssen, Roel; Besselink, Nicolle; Boymans, Sander; de Ligt, Joep; Pedersen, Jakob Skou; Hoeijmakers, Jan; Pothof, Joris; van Boxtel, Ruben; Cuppen, Edwin.

Afiliación

Jager M; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Blokzijl F; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Kuijk E; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Bertl J; Department of Molecular Medicine, Aarhus University, 8200 Aarhus N, Denmark.
Vougioukalaki M; Erasmus Medical Center, 3015 CN Rotterdam, The Netherlands.
Janssen R; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Besselink N; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Boymans S; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
de Ligt J; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Pedersen JS; Department of Molecular Medicine, Aarhus University, 8200 Aarhus N, Denmark.
Hoeijmakers J; Erasmus Medical Center, 3015 CN Rotterdam, The Netherlands.
Pothof J; Erasmus Medical Center, 3015 CN Rotterdam, The Netherlands.
van Boxtel R; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.
Cuppen E; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.

Genome Res ; 29(7): 1067-1077, 2019 07.

Article en En | MEDLINE | ID: mdl-31221724

Asunto(s)

Reparación del ADN/genética; Mutación; Neoplasias/genética; Células Madre Adultas; Animales; Neoplasias de la Mama/genética; Estudios de Cohortes; Análisis Mutacional de ADN; ADN de Neoplasias; Proteínas de Unión al ADN/genética; Endonucleasas/genética; Femenino; Humanos; Ratones; Organoides; Técnicas de Cultivo de Tejidos; Secuenciación Completa del Genoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Reparación del ADN / Mutación / Neoplasias Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: Genome Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos

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